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3-氰基-7-乙氧基香豆素

3-氰基-7-乙氧基香豆素用途

3-Cyano-7-ethoxycoumarin是一种荧光色素P-450底物,酶切时产生蓝色荧光产物。

3-氰基-7-乙氧基香豆素名称

[ CAS 号 ]:
117620-77-6

[ 中文名 ]:
3-氰基-7-乙氧基香豆素

[ 英文名 ]:
3-Cyano-7-ethoxycoumarin

[英文别名 ]:

2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-
MFCD00467359
3-Cyano-7-ethoxycoumarin
7-ethoxy-2-oxochromene-3-carbonitrile
7-Ethoxy-2-oxo-2H-chromene-3-carbonitrile

3-氰基-7-乙氧基香豆素生物活性

[ 描述 ]:

3-Cyano-7-ethoxycoumarin是一种荧光色素P-450底物,酶切时产生蓝色荧光产物。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[相关活性小分子]

3-氰基-7-乙氧基香豆素物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
396.8±42.0 °C at 760 mmHg

[ 熔点 ]:
220-221ºC

[ 分子式 ]:
C₁₂H₉NO₃

[ 分子量 ]:
215.205

[ 闪点 ]:
173.6±18.1 °C

[ 精确质量 ]:
215.058243

[ PSA ]:
63.23000

[ LogP ]:
2.00

[ 外观性状 ]:
黄色至橙色

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.588

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
DMSO: soluble

3-氰基-7-乙氧基香豆素MSDS

详细MSDS(安全技术说明书)

3-氰基-7-乙氧基香豆素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2932209090

3-氰基-7-乙氧基香豆素上下游产品

3-氰基-7-乙氧基香豆素上游产品

3-氰基-7-乙氧基香豆素下游产品

3-氰基-7-乙氧基香豆素海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-氰基-7-乙氧基香豆素文献

Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa.

Xenobiotica 42 , 989-1000, (2012)

1. Frutinone is an active ingredient extracted from the lipophilic fraction of the Polygala Fruticosa demonstrating various antibacterial and fungal properties. The aim of this study was to characteri...

Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity.

Expert Opin. Drug Metab. Toxicol. 10(10) , 1313-24, (2014)

Drug resistance by Plasmodium falciparum remains a challenge in malaria chemotherapy. This paper will focus on physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hy...

Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies.

Xenobiotica 44(7) , 615-26, (2014)

1. Cytochrome P450 enzyme system is the most important contributor to oxidative metabolism of drugs. Modification, and more specifically inhibition, of this system is an important determinant of sever...

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