3-二甲氨基丙胺

3-二甲氨基丙胺用途

【用途一】
广泛用于制造化妆品原料，如棕榈酰胺二甲基丙胺、椰油酰胺丙基甜菜碱、貂油酰胺丙基胺等
【用途二】
N，N-二甲基-1，3-丙二胺是杀菌剂霜霉威的中间体。
【用途三】
用作有机合成中间体，用来制取染料、离子交换树酯、环氧树脂固化剂、油料和无氰电镀锌添加剂、纤维及皮革处理剂和杀菌剂等。该品分子中既含有伯胺基，又有叔胺基，用作环氧树酯固化剂兼具固化剂和促进剂两种功能。主要用于层压品、浇铸品和粘合剂等，一般用量为2-6份。

3-二甲氨基丙胺名称

[ CAS 号 ]:
109-55-7

[ 中文名 ]:
N,N-二甲基-1,3-二氨基丙烷

[ 英文名 ]:
3-Dimethylaminopropylamine

[中文别名 ]:

[英文别名 ]:

EINECS 203-680-9
DMPDA
N1,N1-dimethylpropane-1,3-diamine
N,N-Dimethyl-1,3-propanediamine
3-(dimethylamino)-n-propylamine
3-(Dimethylamino)propylamine
N,N-dimethyl-1,3-diamino-propane
FENTAMINE DMAPA
N,N-dimethylamino-3-aminopropane
U-CAT 2000

3-二甲氨基丙胺物理化学性质

[ 密度 ]:
0.81

[ 沸点 ]:
133 ºC

[ 熔点 ]:
-60 °C

[ 分子式 ]:
C₅H₁₄N₂

[ 分子量 ]:
102.178

[ 闪点 ]:
32 ºC

[ 精确质量 ]:
102.115700

[ PSA ]:
29.26000

[ LogP ]:
-0.29

[ 外观性状 ]:
无色液体

[ 蒸汽密度 ]:
3.6 (vs air)

[ 蒸汽压 ]:
10.1±0.2 mmHg at 25°C

[ 折射率 ]:
1.434-1.436

[ 储存条件 ]:
库房通风低温干燥,与氧化剂,酸类分开储运

[ 水溶解性 ]:
SOLUBLE

[ 凝固点 ]:
-70℃

3-二甲氨基丙胺MSDS

详细MSDS(安全技术说明书)

3-二甲氨基丙胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX7525000

CHEMICAL NAME :: 1,3-Propanediamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 109-55-7

BEILSTEIN REFERENCE NO. :: 0605293

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C5-H14-N2

MOLECULAR WEIGHT :: 102.21

WISWESSER LINE NOTATION :: Z3N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/15/1971 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1870 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 600 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/15/1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83852 No. of Facilities: 126 (estimated) No. of Industries: 5 No. of Occupations: 11 No. of Employees: 998 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83852 No. of Facilities: 124 (estimated) No. of Industries: 3 No. of Occupations: 7 No. of Employees: 6127 (estimated) No. of Female Employees: 119 (estimated)

3-二甲氨基丙胺安全信息

[ 符号 ]:

GHS02, GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H302 + H312-H314-H317-H335

[ 警示性声明 ]:
P210-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P333 + P313-P403 + P235

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive

[ 风险声明 (欧洲) ]:
R10;R22;R34;R43

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2733 3/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
T7525000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29212900

3-二甲氨基丙胺合成路线

详细合成路线

3-二甲氨基丙胺上下游产品

3-二甲氨基丙胺上游产品

3-二甲氨基丙胺下游产品

3-二甲氨基丙胺制备

以二甲氨基丙腈[1738-25-6]为原料在Ni-Al催化剂存在下加氢、甲醇，然后经过滤、精馏，制得3-二甲氨基丙胺成品。所得产品纯度可达99%以上，每吨产品消耗二甲氨基丙腈1150kg。

（1）首先以丙烯腈和二甲胺为原料合成N，N-二甲氨基丙腈，再经加氢而得。

1、二甲氢基丙腈的合成将33%二甲胺水溶液（0.4mol)缓慢地滴加到21.2g（0.4mol)丙烯腈中，滴加过程反应液温度控制在10-15℃滴加时间约为2-3h，再于同一温度下搅拌3-4h，静置过夜。于5.33KPa下减压蒸馏，收集82-84℃馏分，得36.4二甲氨基丙腈中间体产品。

2、二甲基丙二胺的合成将300kg二甲氨基丙腈、1.2g催化剂加入高压釜中，密封，用氮气置换釜中空气3次，然后压入约40g液氨，通入空气，于60-70℃、2.0-3.0MPa下反应1.5h。将反应所得粗产品精馏，即得成品。

（2）在洁净的500ml烧杯中，分别加入丙烯酰胺20g、环氧氯丙烷25ml，并加入NAOH调节反应介质的PH值。于40℃下搅拌反应12h，冷却后，密闭滴加33%的二甲胺水溶液80ml，常温由无水硫酸钠干燥多次，再以三氯甲烷连续萃取多次，得到淡黄色油状液体。产率约82%。干燥后产物溶于少量水，滴加四苯硼酸钠溶液，立即有大量白色沉淀生成，可确认为具有正氮阳离子结构的DMAPA。

3-二甲氨基丙胺海关

[ 海关编码 ]: 2921290000

[ 中文概述 ]:
2921290000. 其他无环多胺及其衍生物及它们的盐. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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