12-羟基硬脂酸
12-羟基硬脂酸用途
12-羟基硬脂酸名称
[ CAS 号 ]:
106-14-9
[ 中文名 ]:
12-羟基十八酸
[ 英文名 ]:
12-hydroxyoctadecanoic acid
[中文别名 ]:
[英文别名 ]:
- MFCD00004592
- DL-12-hydroxystearic acid
- Octadecanoic acid, 12-hydroxy-
- EINECS 203-366-1
- UNII:933ANU3H2S
- 12-Hydroxyoctadecanoic acid
- DL-12-hydroxy stearic acid
- 12-Hydroxystearic acid
12-羟基硬脂酸生物活性
[ 描述 ]:
[ 相关类别 ]:
[体外研究]
[参考文献]
12-羟基硬脂酸物理化学性质
[ 密度 ]:
0.9±0.1 g/cm3
[ 沸点 ]:
436.3±18.0 °C at 760 mmHg
[ 熔点 ]:
80-81ºC
[ 分子式 ]:
C18H36O3
[ 分子量 ]:
300.477
[ 闪点 ]:
231.8±17.7 °C
[ 精确质量 ]:
300.266449
[ PSA ]:
57.53000
[ LogP ]:
6.03
[ 外观性状 ]:
白色粉末
[ 蒸汽压 ]:
0.0±2.4 mmHg at 25°C
[ 折射率 ]:
1.468
[ 储存条件 ]:
−20°C
12-羟基硬脂酸MSDS
12-羟基硬脂酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WI3850000
- CHEMICAL NAME :
- Stearic acid, 12-hydroxy-
- CAS REGISTRY NUMBER :
- 106-14-9
- BEILSTEIN REFERENCE NO. :
- 1726730
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H36-O3
- MOLECULAR WEIGHT :
- 300.54
- WISWESSER LINE NOTATION :
- QV10YQ6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg/40W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 700 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 122,87,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1187 No. of Facilities: 5682 (estimated) No. of Industries: 85 No. of Occupations: 50 No. of Employees: 71848 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1187 No. of Facilities: 5607 (estimated) No. of Industries: 44 No. of Occupations: 38 No. of Employees: 52609 (estimated) No. of Female Employees: 4374 (estimated)
12-羟基硬脂酸安全信息
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi: Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S22-S24/25
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
[ RTECS号 ]:
WI3850000
[ 海关编码 ]:
2942000000
12-羟基硬脂酸合成路线
12-羟基硬脂酸上下游产品
12-羟基硬脂酸上游产品
12-羟基硬脂酸下游产品
12-羟基硬脂酸制备
由蓖麻油在镍-铝催化剂存在下,于185℃和5MPa条件下加氢,反应产物经皂化、酸解即得产品。
12-羟基硬脂酸海关
[ 海关编码 ]: 2918199090
[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸(包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
12-羟基硬脂酸文献
Int. J. Pharm. 486 , 77-87, (2015)
The aim of this work is to study the digestibility of PEG-30-di-(polyhydroxystearate) (Cithrol(®) DPHS) and its semisolid novel self-nanoemulsifying drug delivery systems (SNEDDS). Furthermore, the SN...
Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.Int. J. Pharm. 495 , 972-80, (2015)
In this work, multifunctional lipid nanocapsules (M-LNC) were designed to combine the activity of the cytotoxic drug paclitaxel (PTX) with the immunostimulant CpG. This nanosystem, consisting of modif...
Core-shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effect.Int. J. Pharm. 484(1-2) , 163-71, (2015)
The present paper attempted to develop temperature-sensitive and core-shell structured gel-nanocarriers (gel-NCs) for paclitaxel (PTX) with 12-hydroxystearic acid (12-HSA) as an organic gelator, which...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:12-羟基硬脂酸
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥188.0/5g
¥438.0/25g
联系人:刘佳
产品详情:12-羟基硬脂酸
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥43.0/1g
¥95.0/5g
¥212.0/25g
¥513.0/100g
联系人:夏言
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥58.9/100g
¥102.9/250g
¥29.9/25g
¥190.9/500g
联系人:阿拉丁
产品详情:12-羟基硬脂酸
公司名:中山市迪欣化工有限公司
区域:中山市三角镇
价格:
¥21.5/1000kg
联系人:王洁
产品详情:12-羟基硬脂酸
查看所有供应商请点击:
相关化合物
【12-羟基硬脂酸】化源网提供12-羟基硬脂酸CAS号106-14-9,12-羟基硬脂酸MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询12-羟基硬脂酸上化源网,专业又轻松。>>电脑版:12-羟基硬脂酸
标题:12-羟基硬脂酸_MSDS_用途_密度_CAS号【106-14-9】_化源网 地址:https://www.chemsrc.com/amp/cas/106-14-9_901789.html