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2-金刚烷胺盐酸

2-金刚烷胺盐酸名称

[ CAS 号 ]:
10523-68-9

[ 中文名 ]:
2-金刚烷胺盐酸盐

[ 英文名 ]:
2-adamantaneamine hydrochloride

[中文别名 ]:

盐酸2-金刚烷胺

[英文别名 ]:

Adamantan-2-amine hydrochloride (1:1)
2-adamantaneamine hydrochloride
MFCD00074743
2-Adamantanamine hydrochloride (1:1)
2-Aminoadamantane Hydrochloride
Adamantan-2-amine hydrochloride
EINECS 234-074-2
adamantan-2-amine,hydrochloride

2-金刚烷胺盐酸物理化学性质

[ 沸点 ]:
226.1ºC at 760 mmHg

[ 熔点 ]:
>300 °C(lit.)

[ 分子式 ]:
C₁₀H₁₈ClN

[ 分子量 ]:
187.710

[ 闪点 ]:
96.5ºC

[ 精确质量 ]:
187.112778

[ PSA ]:
26.02000

[ LogP ]:
3.27210

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0831mmHg at 25°C

[ 储存条件 ]:
室温

[ 水溶解性 ]:
soluble

2-金刚烷胺盐酸MSDS

详细MSDS(安全技术说明书)

2-金刚烷胺盐酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU4375100

CHEMICAL NAME :: 2-Adamantanamine, hydrochloride

CAS REGISTRY NUMBER :: 10523-68-9

LAST UPDATED :: 198506

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H17-N.Cl-H

MOLECULAR WEIGHT :: 187.74

WISWESSER LINE NOTATION :: L66 B6/B-H/DI A B- C 1B ITJ AZ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - anticonvulsant

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,313,1980

2-金刚烷胺盐酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S36/37/39-S22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AU4375100

[ 海关编码 ]:
2921300090

2-金刚烷胺盐酸上下游产品

2-金刚烷胺盐酸上游产品

2-金刚烷胺盐酸下游产品

2-金刚烷胺盐酸海关

[ 海关编码 ]: 2921300090

[ 中文概述 ]:
2921300090 其他环（烷，烯，萜烯）单胺或多胺（包括其衍生物及它们的盐）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2-金刚烷胺盐酸文献

Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.

J. Antibiot. 62(1) , 37-41, (2009)

A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine ...

Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.

Biomed. Chromatogr. 20(5) , 423-8, (2006)

Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine...

[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].

Biull. Eksp. Biol. Med. 116(11) , 515-8, (1993)

The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behav...

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