氢溴酸烯丙吗啡

氢溴酸烯丙吗啡名称

[ CAS 号 ]:
1041-90-3

[ 中文名 ]:
氢溴酸烯丙吗啡

[ 英文名 ]:
nalorphine hydrobromide

[英文别名 ]:

氢溴酸烯丙吗啡物理化学性质

[ 沸点 ]:
493.6ºC at 760mmHg

[ 熔点 ]:
208ºC

[ 分子式 ]:
C19H22BrNO3

[ 分子量 ]:
392.28700

[ 闪点 ]:
252.3ºC

[ 精确质量 ]:
391.07800

[ PSA ]:
52.93000

[ LogP ]:
2.65030

[ 蒸汽压 ]:
1.46E-10mmHg at 25°C

氢溴酸烯丙吗啡毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QC7705000
CHEMICAL NAME :
Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide
CAS REGISTRY NUMBER :
1041-90-3
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O3.Br-H
MOLECULAR WEIGHT :
392.33

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
921 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969

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