1041-90-3

• 常用中文名：氢溴酸烯丙吗啡
• 常用英文名：nalorphine hydrobromide
• CAS号：1041-90-3
• 分子式：C₁₉H₂₂BrNO₃
• 分子量：392.28700
• 相关类别： 原料药 专科用药 解毒药
• 发布时间：2018-02-20 08:00:00
• 更新时间：2025-08-25 18:09:12

名称

• 中文名: 氢溴酸烯丙吗啡
• 英文名: (4R,4aR,7S,7aR,12bS)-9-methoxy-3-prop-2-enyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol,hydrobromide
• 英文别名: N-Allylnormorphine hydrobromide; Nalorphine hydrobromide; C19H21NO3.HBr; Nalorphine bromide; EINECS 213-868-2

物化性质

• 沸点: 493.6ºC at 760mmHg
• 熔点: 208ºC
• 分子式: C₁₉H₂₂BrNO₃
• 分子量: 392.28700
• 闪点: 252.3ºC
• 精确质量: 391.07800
• PSA: 52.93000
• LogP: 2.65030
• 蒸汽压: 1.46E-10mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QC7705000 CHEMICAL NAME : Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide CAS REGISTRY NUMBER : 1041-90-3 LAST UPDATED : 199512 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H21-N-O3.Br-H MOLECULAR WEIGHT : 392.33 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 260 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 921 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969