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2-环己胺基乙磺酸(CHES)

2-环己胺基乙磺酸(CHES)用途

CHES(N-环己基牛磺酸)是一种两性离子缓冲剂。CHES(N-环己基牛磺酸)可以与血凝素(HA)结合,模拟唾液酸(SA)和受体结合位点(RBS)-靶向广泛中和抗体[1]。

2-环己胺基乙磺酸(CHES)名称

[ CAS 号 ]:
103-47-9

[ 中文名 ]:
2-环己胺基乙磺酸

[ 英文名 ]:
CHES (Buffer)

[中文别名 ]:

[英文别名 ]:

N-Cyclohexyltaurine
N-(2-Cyclohexylamino)ethanesulfonic acid
2-(N-Cyclohexylamino)ethanesulphonic acid
MFCD00003835
N-cyclohexyl-2-aminoethanesulfonic acid
CHES
Ethanesulfonic acid, 2-(cyclohexylamino)-
2-(N-Cyclohexylamino)Ethanesulfonic Acid
CHES (Buffer)
EINECS 203-115-6

2-环己胺基乙磺酸(CHES)生物活性

[ 描述 ]:

CHES(N-环己基牛磺酸)是一种两性离子缓冲剂。CHES(N-环己基牛磺酸)可以与血凝素(HA)结合,模拟唾液酸(SA)和受体结合位点(RBS)-靶向广泛中和抗体[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Zhaoyu Chen, et al. Small Molecule Inhibitors of Influenza Virus Entry. Pharmaceuticals (Basel). 2021 Jun 18;14(6):587.

2-环己胺基乙磺酸(CHES)物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 熔点 ]:
≥300 °C

[ 分子式 ]:
C₈H₁₇NO₃S

[ 分子量 ]:
207.290

[ 精确质量 ]:
207.092911

[ PSA ]:
74.78000

[ LogP ]:
-0.17

[ 外观性状 ]:
白色结晶粉末

[ 折射率 ]:
1.519

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
Soluble

2-环己胺基乙磺酸(CHES)MSDS

2-环己胺基乙磺酸(CHES)安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
29213099

2-环己胺基乙磺酸(CHES)合成路线

2-环己胺基乙磺酸(CHES)上下游产品

2-环己胺基乙磺酸(CHES)上游产品

2-环己胺基乙磺酸(CHES)下游产品

2-环己胺基乙磺酸(CHES)制备

由2,5-二甲基呋喃水解而得。另一个合成方法是乙酰乙酸乙酯钠与纯碘反应生成二乙酰琥珀酸二乙酯，再将其与10%氢氧化钠溶液进行水解。用无水碳酸钾使反应液饱和，析出丙酮基丙酮。用乙醚提取，从提取液蒸去乙醚后，蒸馏剩余物，收集192-194℃馏分得无色产品。

2-环己胺基乙磺酸(CHES)海关

[ 海关编码 ]: 2921300090

[ 中文概述 ]:
2921300090 其他环（烷，烯，萜烯）单胺或多胺（包括其衍生物及它们的盐）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2-环己胺基乙磺酸(CHES)文献

Polyoxometalates--potent and selective ecto-nucleotidase inhibitors.

Biochem. Pharmacol. 93(2) , 171-81, (2015)

Polyoxometalates (POMs) are inorganic cluster metal complexes that possess versatile biological activities, including antibacterial, anticancer, antidiabetic, and antiviral effects. Their mechanisms o...

The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance.

J. Am. Chem. Soc. 137 , 13556-65, (2015)

We report the first direct electrochemical characterization of the impact of oxygen on the hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase: hydrogenase I from Py...

Low cost referenced luminescent imaging of oxygen and pH with a 2-CCD colour near infrared camera.

Analyst 139(19) , 4924-33, (2014)

A low cost imaging set-up for optical chemical sensors based on NIR-emitting dyes is presented. It is based on a commercially available 2-CCD colour near infrared camera, LEDs and tailor-made optical ...

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