对苯二甲酰氯

对苯二甲酰氯用途

【用途一】
是合成特种纤维的单体，可作芳纶、锦纶增强剂，也可作有机合成原料
【用途二】
对苯二甲酰氯和间苯二甲酰氯有许多相似的用途，也是聚酰胺、聚酯等聚合物的原料。全芳香族聚酰胺纤维作为一种耐热性阻燃纤维，引起人们广泛关注。该品也用作农药、医药、染料、颜料、紫外线吸收剂、交联剂的中间体。
【用途三】
农药；医药；染料；颜料；紫外线吸收剂；交联剂的中间体。

对苯二甲酰氯名称

[ CAS 号 ]:
100-20-9

[ 中文名 ]:
对苯二甲酰氯

[ 英文名 ]:
Terephthaloyl Chloride

[中文别名 ]:

苯二甲醯二氯

[英文别名 ]:

Terephthaloyl dichloride
EINECS 202-829-5
p-Phthaloyl chloride
benzene-1,4-dicarbonyl dichloride
Terephthaloyl Chloride
1,4-Benzenedicarbonyl dichloride
MFCD00000693

对苯二甲酰氯物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
266.0±0.0 °C at 760 mmHg

[ 熔点 ]:
79-81 °C(lit.)

[ 分子式 ]:
C₈H₄Cl₂O₂

[ 分子量 ]:
203.022

[ 闪点 ]:
143.1±18.2 °C

[ 精确质量 ]:
201.958832

[ PSA ]:
34.14000

[ LogP ]:
2.63

[ 外观性状 ]:
白色固体。

[ 蒸汽密度 ]:
7 (vs air)

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.571

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
REACTS

对苯二甲酰氯MSDS

对苯二甲酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WZ1797000

CHEMICAL NAME :: Terephthaloyl chloride

CAS REGISTRY NUMBER :: 100-20-9

BEILSTEIN REFERENCE NO. :: 0607796

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C8-H4-Cl2-O2

MOLECULAR WEIGHT :: 203.02

WISWESSER LINE NOTATION :: GVR DVG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,475,1969

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/m3/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533726

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2140 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(12),35,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 950 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(12),35,1984

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533726 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4168 mg/kg/26W-I

TOXIC EFFECTS :: Liver - other changes

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(12),40,1984 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4122 mg/kg

SEX/DURATION :: male 26 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(12),35,1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4122 mg/kg

SEX/DURATION :: female 26 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 49(12),35,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4188 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 212 (estimated)

对苯二甲酰氯安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H331

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C,T

[ 风险声明 (欧洲) ]:
R34:Causes burns. R23:Toxic by inhalation.

[ 安全声明 (欧洲) ]:
S26-S27-S36/37/39-S45-S38-S28B

[ 危险品运输编码 ]:
UN 2923 8/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
WZ1797000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2917399090

对苯二甲酰氯合成路线

对苯二甲酰氯上下游产品

对苯二甲酰氯上游产品

对苯二甲酰氯下游产品

对苯二甲酰氯制备

对二甲苯进行光催化氯化制得对二（三氯甲基）苯，再与对苯二甲酸加热回流进行酰氯化反应，再用固体碳酸钠调至碱性，滤除氯化钠后，将液体减压蒸馏，收集６８～７５℃（１．８６６ｋＰａ）馏分即得。

对苯二甲酰氯海关

[ 海关编码 ]: 2917399090

[ 中文概述 ]:
2917399090 其他芳香多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917399090 aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

对苯二甲酰氯文献

Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.

PLoS ONE 10 , e0134526, (2015)

As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chlo...

Synthesis of polymer-type chiral stationary phases and their enantioseparation evaluation by high-performance liquid chromatography.

Chirality 19(2) , 129-40, (2007)

Two new chiral polymers of different molecular weights were synthesized by the copolymerization of (1R,2R)-(+)-1,2-diphenylethylenediamine, phenyl diisocyanate and terephthaloyl chloride. The polymers...

Polyamide microcapsules containing jojoba oil prepared by inter-facial polymerization.

J. Microencapsul. 22(5) , 471-86, (2005)

Jojoba oil containing polyamide microcapsules having diameter of approximately 5 microm were prepared by inter-facial polycondensation by direct method (oil-in-water). Qualitative effects of both the ...

更多文献