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Single-Step LRET Aptasensor for Rapid Mycotoxin Detection 10.1021/acs.analchem.7b02368 2017-12-20 Contamination of foods by mycotoxins is a common yet serious problem. Owing to the increase in consumption of fresh produce, consumers have become aware of food safety issues caused by mycotoxins. Therefore, rapid and sensitive mycotoxin detection is in great...
Molecular Engineering of α-Substituted Acrylate Ester Template for Efficient Fluorescence Probe of Hydrogen Polysulfides 10.1021/acs.analchem.7b03755 2017-12-20 In this article, hydrogen polysulfide (H2Sn)-mediated Michael addition/cyclization cascade reactions toward acrylate ester analogues were exploited and utilized to construct novel and robust H2Sn-specific fluorescence probe for the first time. Through rationa...
Collection Method for Isotopic Analysis of Gaseous Nitrous Acid 10.1021/acs.analchem.7b03561 2017-12-20 The sources and chemistry of gaseous nitrous acid (HONO) in the environment are of great interest. HONO is a major source of atmospheric hydroxyl radical (OH), which impacts air quality and climate. HONO is also a major indoor pollutant that threatens human h...
N-Phenyl-2-naphthylamine as a Novel MALDI Matrix for Analysis and in Situ Imaging of Small Molecules 10.1021/acs.analchem.7b02710 2017-12-20 Due to its strong ultraviolet absorption, low background interference in the small molecular range, and salt tolerance capacity, N-phenyl-2-naphthylamine (PNA) was developed as a novel matrix in the present study for analysis and imaging of small molecules by...
Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in Suspension 10.1021/acs.analchem.7b02528 2017-12-20 Many applications of nano- and microparticles require molecular functionalization. Assessing the heterogeneity of a colloidal sample in terms of its molecular functionalization is highly desirable but not accessible by conventional ensemble experiments. Retri...
Soluble Molecularly Imprinted Polymer-Based Potentiometric Sensor for Determination of Bisphenol AF 10.1021/acs.analchem.7b03432 2017-12-19 Molecularly imprinted polymer (MIP)-based polymeric membrane potentiometric sensors have been successfully developed for determination of organic compounds in their ionic and neutral forms. However, most of the MIP receptors in potentiometric sensors develope...
Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol 10.1021/acs.analchem.7b04256 2017-12-19 Telomerase is a key enzyme for maintaining the telomere length and is regarded as a versatile cancer biomarker and a potential drug target due to its important role in cancer and aging. It is necessary to develop a sensitive and reliable method for detection ...
Exonuclease III-Assisted Upconversion Resonance Energy Transfer in a Wash-Free Suspension DNA Assay 10.1021/acs.analchem.7b04240 2017-12-19 Sensitivity is the key in optical detection of low-abundant analytes, such as circulating RNA or DNA. The enzyme Exonuclease III (Exo III) is a useful tool in this regard; its ability to recycle target DNA molecules results in markedly improved detection sens...
MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go 10.1021/acs.analchem.7b03544 2017-12-19 Metaproteomics, the mass spectrometry-based analysis of proteins from multispecies samples faces severe challenges concerning data analysis and results interpretation. To overcome these shortcomings, we here introduce the MetaProteomeAnalyzer (MPA) Portable s...
Toxicity Assessment of Iron Oxide Nanoparticles Based on Cellular Magnetic Loading Using Magnetophoretic Sorting in a Trapezoidal Microchannel 10.1021/acs.analchem.7b03875 2017-12-19 To accurately assess potential nanotoxicity on the basis of cellular iron content, the precise separation of cells into subpopulations according to their magnetic nanoparticle loading is of crucial importance. In this study, we developed a microfluidic magnet...

Single-Step LRET Aptasensor for Rapid Mycotoxin Detection

10.1021/acs.analchem.7b02368

2017-12-20

Contamination of foods by mycotoxins is a common yet serious problem. Owing to the increase in consumption of fresh produce, consumers have become aware of food safety issues caused by mycotoxins. Therefore, rapid and sensitive mycotoxin detection is in great...

Molecular Engineering of α-Substituted Acrylate Ester Template for Efficient Fluorescence Probe of Hydrogen Polysulfides

10.1021/acs.analchem.7b03755

2017-12-20

In this article, hydrogen polysulfide (H2Sn)-mediated Michael addition/cyclization cascade reactions toward acrylate ester analogues were exploited and utilized to construct novel and robust H2Sn-specific fluorescence probe for the first time. Through rationa...

Collection Method for Isotopic Analysis of Gaseous Nitrous Acid

10.1021/acs.analchem.7b03561

2017-12-20

The sources and chemistry of gaseous nitrous acid (HONO) in the environment are of great interest. HONO is a major source of atmospheric hydroxyl radical (OH), which impacts air quality and climate. HONO is also a major indoor pollutant that threatens human h...

N-Phenyl-2-naphthylamine as a Novel MALDI Matrix for Analysis and in Situ Imaging of Small Molecules

10.1021/acs.analchem.7b02710

2017-12-20

Due to its strong ultraviolet absorption, low background interference in the small molecular range, and salt tolerance capacity, N-phenyl-2-naphthylamine (PNA) was developed as a novel matrix in the present study for analysis and imaging of small molecules by...

Simultaneous Rayleigh/Mie and Raman/Fluorescence Characterization of Molecularly Functionalized Colloids by Correlative Single-Particle Real-Time Imaging in Suspension

10.1021/acs.analchem.7b02528

2017-12-20

Many applications of nano- and microparticles require molecular functionalization. Assessing the heterogeneity of a colloidal sample in terms of its molecular functionalization is highly desirable but not accessible by conventional ensemble experiments. Retri...

Soluble Molecularly Imprinted Polymer-Based Potentiometric Sensor for Determination of Bisphenol AF

10.1021/acs.analchem.7b03432

2017-12-19

Molecularly imprinted polymer (MIP)-based polymeric membrane potentiometric sensors have been successfully developed for determination of organic compounds in their ionic and neutral forms. However, most of the MIP receptors in potentiometric sensors develope...

Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol

10.1021/acs.analchem.7b04256

2017-12-19

Telomerase is a key enzyme for maintaining the telomere length and is regarded as a versatile cancer biomarker and a potential drug target due to its important role in cancer and aging. It is necessary to develop a sensitive and reliable method for detection ...

Exonuclease III-Assisted Upconversion Resonance Energy Transfer in a Wash-Free Suspension DNA Assay

10.1021/acs.analchem.7b04240

2017-12-19

Sensitivity is the key in optical detection of low-abundant analytes, such as circulating RNA or DNA. The enzyme Exonuclease III (Exo III) is a useful tool in this regard; its ability to recycle target DNA molecules results in markedly improved detection sens...

MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go

10.1021/acs.analchem.7b03544

2017-12-19

Metaproteomics, the mass spectrometry-based analysis of proteins from multispecies samples faces severe challenges concerning data analysis and results interpretation. To overcome these shortcomings, we here introduce the MetaProteomeAnalyzer (MPA) Portable s...

Toxicity Assessment of Iron Oxide Nanoparticles Based on Cellular Magnetic Loading Using Magnetophoretic Sorting in a Trapezoidal Microchannel

10.1021/acs.analchem.7b03875

2017-12-19

To accurately assess potential nanotoxicity on the basis of cellular iron content, the precise separation of cells into subpopulations according to their magnetic nanoparticle loading is of crucial importance. In this study, we developed a microfluidic magnet...