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醋酸可的松

更新时间:2026-05-09 14:53:48 采购访问:9次

常用名 醋酸可的松 CAS号 50-04-4
价格 ¥需询单/200kg 纯度 98.0%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
Cortisone acetate (17-hydroxy-11-dehydrocorticosterone), a 21-carbon steroid hormone, is one of the main hormones released by the adrenal gland in response to stress.IC50 Value: Target: Glucocorticoid Receptorin vitro: Cortisone suppressed this apoptosis at a concentration range of 1-10,000 ng/ml (2.8-28,000 nM) dose-dependently. Suppression of cortisol-induced apoptosis by cortisonewas consistently observed in PBMCs derived from 16 healthy subjects. Examination for inhibitory activities of the steroids against [3H]dexamethasone binding to PBMCs suggested that cortisone can bind cellular GC-receptors (GC-Rs), but the affinity of cortisone to GCRs is 1/30 or less than that of cortisol [1]. Apoptosis was also readily induced in primary cultures of third trimester decidual cells when treated with cortisol, cortisone, or dexamethasone (all 100 nM for 24 h) [2]. in vivo: The effects of a single dose of cortisone acetate (5 or 10 mg/100 g body weight) on B cells were examined in young chickens. A dose-dependent increase in numbers of circulating B lymphocytes and a change in their Ig-class distribution were followed by parallel increase in splenic plasma cells and serum immunoglobulins. The higher dose of cortisone produced changes in Bmu and Bgamma cells, whereas the lower dose primarily affected Bmu cells [3]. Adult female CD-1 mice received daily injections of cortisone acetate (0--50 mg/kg subcutaneously) and/or amphotericin B (0--12.5 mg/kg intraperitoneally) in a checkerboard combination dosage pattern for 30 days. Dosages of amphotericin B and cortisone acetate that produced little or no mortality individually produced significant (P less than 0.005) mortality in combination [4].Toxicity: Oral use of cortisone has a number of potential systemic side-effects: hyperglycemia, insulin resistance, diabetes mellitus, osteoporosis, anxiety, depression, amenorrhoea, cataracts and glaucoma, among other problems.
物理化学性质:
CAS号:50-04-4
常用中文名:醋酸可的松
常用英文名:Cortisone acetate
分子式:C23H30O6
分子量:402.481
密度:1.3±0.1 g/cm3
沸点:577.3±50.0 °C at 760 mmHg
熔点:237-240 °C(lit.)
闪点:197.3±23.6 °C
储存条件:室温

供应商信息

苏州市森菲达化工有限公司 认证供应商

认证状态:已认证供应商
商品数:20000件
电话:0512-18796480002
地址:苏州市高新区浒墅关经济技术开发区
地区: 江苏省 苏州市 相城区
联系人:程经理
联系人电话:18796480002
邮件:13771713870@163.com
网址:http://www.senfeida.com
主要市场:国内,海外
年贸易额:
外贸占销售比例:
主要合作伙伴:
苏州市森菲达化工有限公司,位于苏州市高新区浒墅关经济技术开发区。是由一群高分子精细化工专业人员组建而成的,专为客户提供配套化学原料。为解决客户的实质问题,我们专注于引入新产品,带入新思路,尤在 3D打印、UV光固化方面有先进的功能性原材料和强大的技术后盾。 自有的合成研发团队与应用实验室,并投资入股在湖南岳阳的化工厂,长期定制**。


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参考价格:¥198/5g
其他供应商价格:
2022-02-19 Cortisone Acetate
价格:¥72.9
2019-03-05 醋酸可的松
价格:¥198.0
2024-09-13 醋酸可的松
价格:¥需询单
2022-09-16 醋酸可的松
价格:¥1000.0
2023-11-18 Cortisone acetate
价格:¥需询单
2018-05-08 醋酸可的松
价格:¥需询单
2018-07-28 醋酸可的松 50-04-4
价格:¥需询单
2024-04-16 醋酸可的松,醋可
价格:¥需询单
2024-05-16 醋酸可的松
价格:¥需询单

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