| 常用名 | 艾洛利单抗 | CAS号 | 2489390-15-8 |
|---|---|---|---|
| 价格 | ¥需询单/1g ¥需询单/5g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: KY-1044 (Alomfilimab; SAR 445256) is a fully human IgG1 antibody targeting inducible costimulatory receptor (ICOS). KY-1044 depletes ICOShigh cells via antibody-dependent cellular cytotoxicity (ADCC) through the engagement of FcgRIIIa. KY-1044 act as a costimulatory molecule on cells expressing lower ICOS levels, such as CD8+ TEff cells (through FcgR-dependent clustering). KY-1044 exploit the differential expression of ICOS on T-cell subtypes to improve the intratumoral immune contexture and restore an antitumor immune response[1]. 物理化学性质: CAS号:2489390-15-8 常用中文名:艾洛利单抗 常用英文名:KY-1044 分子式: 分子量: 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |