| 常用名 | 安五脂素 | CAS号 | 107534-93-0 |
|---|---|---|---|
| 价格 | ¥需询单/5mg ¥需询单/20mg ¥需询单/100mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 999 |
| 产品详情(用途,包装等)
用途: Macelignan(Anwuligan) is a natural compound isolated from Myristica fragrans Houtt; possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation.IC50 value:Target: in vitro: Macelignan significantly attenuated the ROS production and neurotoxicity induced by glutamate in HT22 cell [1]. At 24 h of biofilm growth, S. mutans, A. viscosus and S. sanguis biofilms were reduced by up to 30%, 30% and 38%, respectively, after treatment with 10 microg/mL macelignan for 5 min [2]. Cisplatin-induced phosphorylation of c-Jun N-terminal kinase1/2 (JNK1/2) and extracellular signal-regulated kinase1/2 (ERK1/2) was abrogated by pretreatment with macelignan, however, that of p38 was not significantly affected [3].in vivo: Macelignan attenuated the expression of phosphorylated c-Jun in cisplatin-treated mice [3]. Daily administration of macelignan reduced the spatial memory impairments induced by the chronic LPS infusions [4]. 物理化学性质: CAS号:107534-93-0 常用中文名:安五脂素 常用英文名:Anwulignan 分子式:C20H24O4 分子量:328.402 密度:1.159 沸点:467.0±40.0 °C at 760 mmHg 熔点:70-71℃ 闪点:236℃ 储存条件:-20°C |