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14-3-3 inhibitor BV2

更新时间:2024-07-17 16:21:03 采购访问:13次

常用名 14-3-3 inhibitor BV2 CAS号 302602-92-2
价格 ¥需询单/100mg ¥需询单/250mg ¥需询单/1g 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
A novel nonpeptidic inhibitor of 14-3-3 protein-protein interaction that promotes the apoptotic death of cells expressing either wt Bcr-Abl construct or T315I mutation; induces significant dose-dependent reduction of reproductive integrity of Ba/F3 cells expressing the wt and T315I-mutated Bcr-Abl with LD50 of 1.04 and 1.47 uM, respectively; promoted c-Abl release from 14-3-3σ, abolishes c-Abl expression in the cytoplasm, but has no influence on 14-3-3σ levels, induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib.
物理化学性质:
CAS号:302602-92-2
常用中文名:14-3-3 inhibitor BV2
常用英文名:14-3-3 inhibitor BV2
分子式:C20H17N3O6
分子量:395.366
密度:1.5±0.1 g/cm3
沸点:N/A
熔点:N/A
闪点:N/A

供应商信息

上海念兴实业有限公司 认证供应商

认证状态:已认证供应商
商品数:403768件
电话:18916513247
地址:2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
网址:http://www.echemcloud.com
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2022-11-29 14-3-3 inhibitor BV2
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