L-(-)-α-Methyldopa hydrochloride
更新时间：2025-09-01 20:31:59
采购访问：20次
| 常用名 | L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐 | CAS号 | 884-39-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.Target: alpha-adrenergic agonistMethyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. However, it continues to have a role in otherwise difficult to treat hypertension and gestational hypertension (also known as pregnancy-induced hypertension (PIH)).Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, also known as aromatic L-amino acid decarboxylase, which converts L-DOPA into dopamine. Dopamine is a precursor for norepinephrine (noradrenaline) and subsequently epinephrine (adrenaline). This inhibition results in reduced dopaminergic and adrenergic neurotransmission in the peripheral nervous system. This effect may lower blood pressure and cause central nervous system effects such as depression, anxiety, apathy, anhedonia, and parkinsonism. It is converted to α-methylnorepinephrine by dopamine beta-hydroxylase (DBH). α-methylnorepinephrine is an agonist of presynaptic central nervous system α2-adrenergic receptors. Activation of these receptors in the brainstem appears to inhibit sympathetic nervous system output and lower blood pressure. This is also the mechanism of action of clonidine. 物理化学性质： CAS号：884-39-9 常用中文名：L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐 常用英文名：L-(-)-α-Methyldopa (hydrochloride) 分子式：C10H14ClNO4 分子量：247.67500 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
上海化源生化科技有限公司
认证状态：已认证供应商
商品数：396718件
电话：53555033
地址：上海市普陀区金沙江路1759号圣诺亚大厦B座508室
地区： 上海市 上海市 普陀区
联系人：化源网
联系人电话：133 1186 9306
邮件：xuqm@chemsrc.com
网址：http://www.chemsrc.com
主要市场：
年贸易额：
外贸占销售比例：
主要合作伙伴：
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：L-(-)-α-Methyldopa hydrochloride
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：化源网
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：L-(-)-α-Methyldopa hydrochloride
- 价格： ￥469.0/500mg ￥589.0/1g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
查看所有供应商和价格请点击：
L-3-(3,4-二羟基苯基)-2-甲基丙氨酸盐酸盐生产厂家
参考价格：$60/1g