| 常用名 | YC-001 | CAS号 | 748778-73-6 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: YC-001 is a novel pharmacological chaperone of rod photoreceptor opsin, rescues the transport of multiple rod opsin mutants in mammalian cells; demonstrates micromolar potency and efficacy greater than 9-cis-retinal with lower cytotoxicity; binds to bovine rod opsin with an EC50 (8.7 uM) similar to 9-cis-retinal, improves the glycosylation of the P23H-opsin mutant; YC-001 is an inverse agonist and antagonist of rod opsin that non-competitively antagonizes rod opsin signaling, delays isorhodopsin pigment regeneration; protects Abca4 -/- Rdh8 -/- mice from bright light-induced retinal degeneration. 物理化学性质: CAS号:748778-73-6 常用中文名:YC-001 常用英文名:YC-001 分子式:C12H7ClO2S2 分子量:282.766 密度:1.5±0.1 g/cm3 沸点:494.2±45.0 °C at 760 mmHg 熔点:N/A 闪点:252.7±28.7 °C |