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RSV604

更新时间:2025-09-09 08:03:12 采购访问:20次

常用名 RSV604 CAS号 676128-63-5
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
RSV604 is a novel inhibitor of respiratory syncytial virus replication(EC50=0.86 uM); a putative RSV nucleoprotein(N) inhibitor in phase 2 clinical trials.IC50 value: 0.86 uM(EC50) [1]Target: RSV inhibitorRSV604, a novel benzodiazepine with submicromolar anti-RSV activity. It proved to be equipotent against all clinical isolates tested of both the A and B subtypes of the virus. The compound has a low rate of in vitro resistance development. Sequencing revealed that the resistant virus had mutations within the nucleocapsid protein. This is a novel mechanism of action for anti-RSV compounds. In a three-dimensional human airway epithelial cell model, RSV604 was able to pass from the basolateral side of the epithelium effectively to inhibit virus replication after mucosal inoculation. RSV604, which is currently in phase II clinical trials, represents the first in a new class of RSV inhibitors and may have significant potential for the effective treatment of RSV disease.
物理化学性质:
CAS号:676128-63-5
常用中文名:RSV604
常用英文名:RSV-604
分子式:C22H17FN4O2
分子量:388.39400
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

上海化源世纪贸易有限公司 认证供应商

认证状态:已认证供应商
商品数:396716件
电话:53555033
地址:上海市普陀区金沙江路1759号圣诺亚大厦B座
地区: 上海市 上海市 普陀区
联系人:徐经理
联系人电话:13311869306
邮件:xuqm@chemsrc.com
网址:http://www.chemsrc.com
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参考价格:$77/10mM*1mLinDMSO
其他供应商价格:
2024-03-12 RSV604
价格:¥6797.9
2023-09-26 RSV604
价格:¥需询单
2021-04-03 RSV-604
价格:¥2100.0

查看所有价格,请点击RSV604价格