盐酸阿米替林
更新时间：2025-08-31 18:09:34
采购访问：33次
| 常用名 | 盐酸阿米替林 | CAS号 | 549-18-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Amitriptyline Hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA).Target: OthersAmitriptyline acts primarily as a serotonin-norepinephrine reuptake inhibitor, with strong actions on the serotonin transporter and moderate effects on the norepinephrine transporter. It has negligible influence on the dopamine transporter and therefore does not affect dopamine reuptake, being nearly 1,000 times weaker on it than on serotonin [1]. Amitriptyline additionally functions as a 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, 5-HT7, α1-adrenergic, H1, H2, and mACh receptorantagonist, and σ1 receptor agonist. It has also been shown to be a relatively weak NMDA receptor negative allosteric modulator at the same binding site as phencyclidine. Amitriptyline inhibits sodium channels, L-type calcium channels, and Kv1.1, Kv7.2, and Kv7.3 voltage-gated potassium channels, and therefore acts as a sodium, calcium, and potassium channel blocker as well [2]. Recently, amitriptyline has been demonstrated to act as an agonist of the TrkA and TrkB receptors. It promotes the heterodimerization of these proteins in the absence of NGF and has potent neurotrophic activity both in-vivo and in-vitro in mouse models [3]. 物理化学性质： CAS号：549-18-8 常用中文名：盐酸阿米替林 常用英文名：Amitriptyline Hydrochloride 分子式：C20H24ClN 分子量：313.864 密度：1.076g/cm3 沸点：398.2ºC at 760 mmHg 熔点：196-197°C 闪点：11 °C 储存条件：2-8°C |
上海化源世纪贸易有限公司
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- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸阿米替林
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：盐酸阿米替林
- 价格： ￥37.9/1g ￥104.9/5g ￥1038.9/1ml ￥1152.9/100g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥101/5g