| 常用名 | MMRi64 | CAS号 | 430458-66-5 |
|---|---|---|---|
| 价格 | 纯度 | 99.61% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: MMRi64 is a small molecule inhibitor that disrupts Mdm2-MdmX RING-RING interaction interactions in vitro and activates p53 in cancer cells; potently induces downregulation of Mdm2 and MdmX in leukemia cells, only induces the expression of pro-apoptotic gene PUMA (p53 upregulated modulator of apoptosis) with minimal induction of growth-arresting gene p21; selectively induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells; synergistically induces p53 and apoptosis in combination with Nutlin3a. 物理化学性质: CAS号:430458-66-5 常用中文名:MMRi64 常用英文名:MMRi64 分子式:C22H17Cl2N3O 分子量:410.298 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |