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(2S,5R,6R)-3,3-二甲基-7-氧代-6-((R)-2-(2-氧代咪唑啉-1-甲酰胺基)-2-苯乙酰胺基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸钠

更新时间:2025-08-26 16:51:38 采购访问:29次

常用名 阿洛西林钠 CAS号 37091-65-9
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Azlocillin is an acylampicillin with a broad spectrum against bacteria.Target: AntibacterialAzlocillin (12.5 μg/mL) inhibits over 75% of the isolates of Pseudomonas aeruginosa. Azlocillin (12.5 μg/mL) is also active against indole-negative and -positive Proteus spp., inhibiting 98 and 71%, respectively. Azlocillin is more active than mezlocillin, ticarcillin, and carbenicillin and as active as BLP-1654 against isolates of P. aeruginosa [1]. The acyl side chains of Azlocillin have an ureido-(urea) structurehence the name "ureidopenicillins" or, more specifically, "acylureidopenicillins." In vitro studies against P. aeruginosa demonstrates that piperacillin has activity that is twice that of azlocillin, 4 times that of mezlocillin and ticarcillin, and about 8 times that of carbenicillin. Azlocillin produces elongated bacterial forms with delayed or no lysis in morphologic studies [2].Azlocillin has MICs of 12.5 μg/mL on Pseudomonas aeruginosa. Azlocillin (3.125 μg/mL) results in a reduction in the rate of growth but no bactericidal phase on Pseudomonas aeruginosa. Azlocillin decreases an initial lag phase with increasing drug concentration. At the lower concentration of tobramycin (0.5 μg/ml), the combinations with both the high and the low concentrations of Azlocillin are more effective than the individual components on Pseudomonas aeruginosa [3]. Isolates with derepression of AmpC enzyme are one to two doubling dilutions more resistant to azlocillin than are those in which increased efflux or impermeability is inferred. Those with secondary β-lactamases are mostly (12/14 cases) susceptible to ceftazidime at 4 mg/L, but are amongst the most resistant to Azlocillin (MIC ≥128 mg/L in 10/14 cases) [4].
物理化学性质:
CAS号:37091-65-9
常用中文名:阿洛西林钠
常用英文名:Azlocillin sodium salt
分子式:C20H22N5NaO6S
分子量:483.473
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8°C

供应商信息

上海化源生化科技有限公司 认证供应商

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商品数:396715件
电话:53555033
地址:上海市普陀区金沙江路1759号圣诺亚大厦B座508室
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联系人:徐经理
联系人电话:133 1186 9306
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参考价格:$106/10mM*1mLinDMSO
其他供应商价格:
2019-03-05 阿洛西林钠
价格:¥788.0
2022-11-29 Azlocillin sodium salt
价格:¥需询单
2021-02-06 Azlocillin sodium salt
价格:¥489.0
2022-02-19 Azlocillin sodium salt
价格:¥2108.9
2016-11-05 阿洛西林钠
价格:¥800.0
2024-01-20 阿洛西林钠
价格:¥99.0
2018-10-18 阿洛西林钠
价格:¥需询单
2024-01-09 Azlocillin sodium
价格:$需询单

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