| 常用名 | C-178 | CAS号 | 329198-87-0 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: C-178, a covalent inhibitor of STING, binds to Cys91, potently and selectively suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. C-178 significantly reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity. C-178 blocks palmitoylation (PMA)-induced clustering of STING; inhibits the CMA-induced phosphorylation of TBK1 (downstream protein kinase of STING)[1]. 物理化学性质: CAS号:329198-87-0 常用中文名:C-178 常用英文名:C-178 分子式:C17H10N2O5 分子量:322.27 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20°C,密闭,干燥 |