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克霉唑

更新时间:2025-09-15 11:15:04 采购访问:75次

常用名 克霉唑 CAS号 23593-75-1
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.
物理化学性质:
CAS号:23593-75-1
常用中文名:克霉唑
常用英文名:Clotrimazole
分子式:C22H17ClN2
分子量:344.837
密度:1.1±0.1 g/cm3
沸点:482.3±40.0 °C at 760 mmHg
熔点:147-149ºC
闪点:245.5±27.3 °C
储存条件:Store at RT.

供应商信息

上海化源世纪贸易有限公司 认证供应商

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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
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