| 常用名 | AS2863619 | CAS号 | 2241300-51-4 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC50s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene[1]. 物理化学性质: CAS号:2241300-51-4 常用中文名:AS2863619 常用英文名:AS2863619 分子式:C16H14Cl2N8O 分子量:405.24 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:-20°C |