常用名 | 2BAct | CAS号 | 2143542-28-1 |
---|---|---|---|
价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: 2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays; 2BAct normalized body weight gain and prevented motor deficits in male R191H mice, prevented myelin loss and reactive gliosis in the brain and spinal cord of R191H mice; also prevented ISR induction in the cerebellum and spinal cord of Eif2b5R132H/R132H mice, prevented all measures of pathology and normalizes the transcriptome and proteome of Vanishing White Matter (VWM) mice. 物理化学性质: CAS号:2143542-28-1 常用中文名:2BAct 常用英文名:2BAct 分子式:C19H16ClF3N4O3 分子量:440.807 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |