常用名 | SKI-2852 | CAS号 | 1346554-47-9 |
---|---|---|---|
价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: A highly potent, selective, and orally bioavailable 11β-HSD1 inhibitor with IC50 of 2.9 and 1.6 nM for hHSD1 and mHSD1, respectively; demonstrates no CYP and PXR liabilities, excellent PK profiles across species, and highly potent and sustainable PD activity; significantly reduces blood glucose and HbA1c levels and improves the lipid profiles in ob/ob mice, synergistically enhances the HbA1c-lowering effect of metformin in vivo. 物理化学性质: CAS号:1346554-47-9 常用中文名:SKI-2852 常用英文名:SKI-2852 分子式:C27H34FN5O4S 分子量:543.658 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |