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1-羟基吡啶-2-硫酮锌

更新时间:2025-08-27 13:12:48 采购访问:36次

常用名 吡啶硫酮锌 CAS号 13463-41-7
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.Target: Proton PumpZinc pyrithione is considered as a coordination complex of zinc. The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond. Zinc pyrithione, which is a dimer but is probably biologically active as a monomer, induces plasma membrane depolarization with half-maximal effect (K1/2) of about 0.3 mM [1]. Zinc pyrithione is an unusual synthetic potentiator that potently activates both heterologous and native M channels by inducing channel opening at the resting potential [2]. Zinc pyrithione rapidly accumulated in the tissues of the exposed mussels, proportionately to both exposure concentration and time. Even though the 7-d median lethal concentration (LC50) = 8.27 μM established here appears high with respect to reported ZnPT environmental concentrations, the results indicate that this biocide could represent a threat for marine organisms in coastal environments and that further investigations on its biological effects at sublethal doses are needed [3].
物理化学性质:
CAS号:13463-41-7
常用中文名:吡啶硫酮锌
常用英文名:Zinc Pyrithione
分子式:C10H8N2O2S2Zn
分子量:317.722
密度:1.782 g/cm3 (25ºC)
沸点:253.8ºC at 760 mmHg
熔点:262ºC
闪点:107.3ºC
储存条件:室温

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参考价格:$73/10mM*1mLinDMSO
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