5-乙基-5-苯基二氢嘧啶-4,6(1H,5H)-二酮
更新时间：2025-08-21 17:04:30
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| 常用名 | 扑米酮 | CAS号 | 125-33-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Primidone is an anticonvulsant of the pyrimidinedione class.Target: GABA ReceptorPrimidone is an anticonvulsant of the pyrimidinedione class, the active metabolites of which, phenobarbital (minor) and phenylethylmalonamide (PEMA) (major), are also anticonvulsants. It is believed to work via interactions with voltage-gated sodium channels which inhibit high-frequency repetitive firing of action potentials [1]. The effect of primidone in essential tremor is not mediated by PEMA.[76] The major metabolite, phenobarbital, is also a potent anticonvulsant in its own right and likely contributes to primidone's effects in many forms of epilepsy [2]. Primidone and the other enzyme-inducing anticonvulsants can cut the half-life of antipyrine roughly in half (6.2 ± 1.9 h vs. 11.2 ± 4.2 h), and increases the clearance rate by almost 70%. Phenobarbital reduces the half-life to 4.8 ± 1.3 and increases the clearance by almost 109% [3]. 物理化学性质： CAS号：125-33-7 常用中文名：扑米酮 常用英文名：Primidone 分子式：C12H14N2O2 分子量：218.25200 密度：1.138g/cm3 沸点：520.7ºC at 760mmHg 熔点：281-282°C 闪点：228.2ºC 储存条件：Store at RT |
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- 产品名：扑米酮
- 价格： ￥151.9/5g ￥389.9/1ml ￥1410.9/100g ￥405.9/25g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$79/10mM*1mLinDMSO