| 常用名 | HAMI3379 | CAS号 | 1245653-57-9 |
|---|---|---|---|
| 价格 | 纯度 | 95.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: HAMI3379 (HAMI-3379) is a potent and selective antagonist of cysteinyl leukotriene 2 (CysLT(2)) receptor, inhibits LTD4- and LTC4-induced intracellular calcium mobilization withIC50 of 3.8 nM and 4.4 nM respectively; exhibits very low potency on a recombinant CysLT(1) receptors (IC50>10 uM), does not exhibit any agonistic activity on both CysLT receptors; concentration-dependently inhibits and reverses the LTC(4)-induced perfusion pressure increase and contractility decrease in isolated Langendorff-perfused guinea pig hearts, protects against acute brain injury after focal cerebral ischemia in rats. 物理化学性质: CAS号:1245653-57-9 常用中文名:HAMI3379 常用英文名:HAMI3379 分子式:C34H45NO8 分子量:595.733 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |