依普利酮
更新时间：2025-08-20 09:59:06
采购访问：116次
| 常用名 | 依普利酮 | CAS号 | 107724-20-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM.Target: Mineralocorticoid ReceptorEplerenone is a selective mineralocorticoid receptor antagonist, which has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. Eplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors [1]. Benefits of eplerenone therapy over placebo were also observed in several secondary outcomes, including: death from any cause or hospitalization for HF; death from any cause; hospitalization for any reason; or hospitalization for HF [2]. 物理化学性质： CAS号：107724-20-9 常用中文名：依普利酮 常用英文名：Eplerenone 分子式：C24H30O6 分子量：414.491 密度：1.3±0.1 g/cm3 沸点：597.9±50.0 °C at 760 mmHg 熔点：241-243ºC 闪点：259.5±30.2 °C 储存条件：0-10°C;避免加热 |
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