常用名 | Helioxanthin 8-1 | CAS号 | 840529-13-7 |
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价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: Helioxanthin 8-1 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 uM.IC50 value: >5/10/1.4/15 uM(HBV/HCV/HSV-1/HIV) [1]Target: Antiviral agentThe cyclic hydrazide 28(Helioxanthin 8-1) showed the most potent antiHBV activity among those helioxanthin analogues tested. In addition, compound 28 exhibited moderately potent activity against HIV. It would therefore be promising to study helioxanthin analogues that contain a six-membered ring instead of the five-membered ring found in the lactam [1]. 8-1 exhibited effective inhibition on DHBV replication. The combination of 8-1 with 3TC resulted in additional anti-DHBV activity. Viral induced cells displayed higher susceptibility to 8-1 treatment than non-induced cells. HBV X protein might not be an essential factor in the initiation of the biological activity of 8-1, as demonstrated by its absence in DHBV [2]. 物理化学性质: CAS号:840529-13-7 常用中文名:Helioxanthin 8-1 常用英文名:Helioxanthin 8-1 分子式:C20H12N2O6 分子量:376.319 密度:1.5±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |