| 常用名 | ZZW-115 | CAS号 | 801991-87-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: ZZW-115 (ZZW115, ZZW 115) is a potent inhibitor of NUPR1 (Kd=2.1 uM), an intrinsically disordered protein (IDP) with an entirely disordered conformation; demonstrates antitumor activity on a panel of 11 primary PDAC-derived cells and it was found to be efficient to kill the cancer cells with IC50 in the range from 0.84 μM (ANOR) to 4.93 μM (HN14), also inhibits the growth of other tumors-derived cells (IC50=0.42 μM (Hep2G cells) to 7.75 μM (SaO-2 cells)); induces pancreatic cell death by necrosis and apoptosis and inhibits the growth pancreatic xenografted tumors in vivo. 物理化学性质: CAS号:801991-87-7 常用中文名:ZZW-115 常用英文名:ZZW-115(ZZW115 分子式:C24H31F3N4S 分子量:464.595 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8°C,密封,干燥 |