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(2'S,4aR,4bS,6aS,7aS,8aS,8bS,8cR,8dR,9aR)-4a,6a-二甲基l-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,8d,9,9a-十四氢-3'H-螺[环丙烷并[4,5]环戊烷并[1,2-a]环丙烷并[l]菲-7,2'-呋喃]-2,5'(3H,4'H)-二酮

更新时间:2025-12-27 18:31:26 采购访问:25次

常用名 屈螺酮 CAS号 67392-87-4
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Drospirenone(Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone.Target: Progesterone ReceptorDrospirenone is a novel progestin under clinical development that is similar to the natural hormone progesterone, combining potent progestogenic with antimineralocorticoid and antiandrogenic activities. drospirenone was devoid of glucocorticoid activity. Both progestins did not show any antiglucocorticoid action. Furthermore, drospirenone and progesterone both showed considerable antimineralocorticoid activity and weak mineralocorticoid activity [1]. the pharmacological profile of drospirenone is more closely related to that of the natural hormone progesterone than is that of any other synthetic progestogen in use today. Therefore, drospirenone is anticipated to give rise to a number of additional health benefits both for users of oral contraceptives and hormone replacement therapy recipients [2]. The combination of 17beta-estradiol and drospirenone has a positive effect on BMD and a potentially beneficial effect on lipids. Although endometrial thickness increased slightly, the safety of the endometrium was assured, as no cases of hyperplasia or cancer occurred [3].Clinical indications: Acne; Dysmenorrhea; Endometriosis; Female contraception; Folic acid deficiency; Premenstrual syndrome
物理化学性质:
CAS号:67392-87-4
常用中文名:屈螺酮
常用英文名:Drospirenone
分子式:C24H30O3
分子量:366.493
密度:1.3±0.1 g/cm3
沸点:552.2±50.0 °C at 760 mmHg
熔点:196-200ºC
闪点:241.6±30.2 °C
储存条件:0-10°C;避免加热

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参考价格:$55/10mM*1mLinDMSO
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