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5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

更新时间:2026-01-05 11:30:17 采购访问:11次

常用名 5-甲氧基-3-(1,2,3,6-四氢吡啶-4-基)-1H-吲哚 CAS号 66611-26-5
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors; IC50 value:Target: 5-HT1A/1B agonistRU 24969 possesses preference for the purported 5-HT1B subtype of central 5-HT1 recognition site. The reported significant linear correlation between hypotensive activity following intravenous (i.v.) administration to anesthetized rats and affinity for the central 5-HT1 binding site could only be maintained by incorporation of the affinity of RU 24969 for its low and 8-OH-DPAT for its high affinity binding site [1]. The drug RU 24969 (10 mg/kg) inhibited the rate of synthesis of 5-HT in rat brain by about 50%. Pretreatment of rats with desmethylimipramine over a longer term or clenbuterol given acutely, treatments known to enhance the behavioural responses of rats to various other 5-HT agonists, did not alter the RU 24969-induced response [2]. RU 24969 (0.03-3.0mg/kg, s.c.) dose-dependently decreased water consumption in water deprived rats [3].
物理化学性质:
CAS号:66611-26-5
常用中文名:5-甲氧基-3-(1,2,3,6-四氢吡啶-4-基)-1H-吲哚
常用英文名:RU 24969
分子式:C14H16N2O
分子量:228.29000
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

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参考价格:$79/10mM*1mLinDMSO
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