2-(1,3-二硫杂环戊二烯-2-亚甲基)丙二酸二异丙酯
更新时间：2024-07-15 12:35:57
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| 常用名 | 马洛替酯 | CAS号 | 59937-28-9 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Malotilate is a liver protein metabolism improved compound, which selectively inhibit the 5-lipoxygenase. IC50 Value:Target: 5-lipoxygenasein vitro: In an in vitro invasion assay using rat lung endothelial (RLE) cells, invasion of tumor cells which had been treated with MT (10 ng/ml, 24 h) was not affected; however, when RLE cells had been treated with MT, invasion was significantly inhibited in three cell lines (SAS, Ca9-22 and HSC-4) and a tendency to inhibition was also observed in other cell lines [1].in vivo: The improvement rates for choline esterase activity were significantly greater in the malotilate group than in the control group. Serum albumin levels significantly increased in the malotilate group but not in the control group [2]. In the rats treated with MT for 19 days after i.v. inoculation of c-SST-2 cells, lung metastasis was also significantly suppressed [3]. Malotilate prevented increases in serum markers of type III and IV collagen synthesis as well as accumulation of the collagens, laminin and fibronectin in the liver [4].Toxicity: Malotilate cytotoxicity to PBMCs, assessed by trypan blue dye exclusion and lactate dehydrogenase (LDH) release into the culture media, was found to be markedly increased by the addition of the NADPH generating system, indicating that metabolites play a significant role in toxicity [5]. 物理化学性质： CAS号：59937-28-9 常用中文名：马洛替酯 常用英文名：Malotilate 分子式：C12H16O4S2 分子量：288.383 密度：1.3±0.1 g/cm3 沸点：321.5±42.0 °C at 760 mmHg 熔点：N/A 闪点：138.7±15.9 °C 储存条件：-20°C |
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- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：2-(1,3-二硫杂环戊二烯-2-亚甲基)丙二酸二异丙酯
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Malotilate
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海脉铂医药科技有限公司
- 上海市 上海市 嘉定区
- 产品名：Malotilate
- 价格： ￥759.0/1g ￥1839.0/100mg ￥429.0/5mg ￥需询单/1g
- 纯度：98.0%
- 备货期：2天
- 联系人：李先生
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：马洛替酯
- 价格： ￥335.9/1g ￥1048.9/1ml ￥1026.9/5g ￥需询单/1g
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$99/10mM*1mLinDMSO