2-(4-(叔丁基)苯基)-1H-苯并[d]咪唑
更新时间：2024-07-15 12:35:27
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| 常用名 | 2-(4-叔丁基苯基)苯并咪唑 | CAS号 | 49671-76-3 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： ZLN005 is a novel transcriptional regulator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).IC50 value:Target: PGC-1αin vitro: ZLN005 increases expression of the PGC-1α gene in L6 myotubes. ZLN005 increased PGC-1α mRNA levels in a dose-dependent manner; 20 μmol/L ZLN005 caused a threefold increase over the control after 24 h. At 10 μmol/L, the PGC-1α mRNA levels were increased to almost the same extent at 16 to 48 h [1]. ZLN005 did not increase the expression of the PGC-1α gene in rat primary hepatocytes. AMP-activated protein kinase is involved in the mechanism inducing PGC-1α in L6 myotubes [1]in vivo: An insulin tolerance test revealed that treatment with ZLN005 significantly decreased insulin resistance in db/db mice, as evidenced by the approximately 18% decrease in the AUC. A PTT also was performed in db/db mice, and ZLN005 improved pyruvate tolerance, as evidenced by the 16% decrease in the AUC. In db/db mice, plasma NEFA and triglyceride levels were decreased by 20% and 37%, respectively, and cholesterol was decreased by 10% with ZLN005 treatment. Plasma insulin and β-hydroxybutyrate content, liver/bodyweight index and adipose composition, and muscle and liver triglyceride levels, however, were not ameliorated by treatment with ZLN005 or metformin [1]. 物理化学性质： CAS号：49671-76-3 常用中文名：2-(4-叔丁基苯基)苯并咪唑 常用英文名：ZLN005 分子式：C17H18N2 分子量：250.338 密度：1.1±0.1 g/cm3 沸点：415.3±38.0 °C at 760 mmHg 熔点：257-258℃ 闪点：205.4±13.2 °C 储存条件：2~8°C，密封 |
上海念兴实业有限公司
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：ZLN005
- 价格： ￥277.9/10mg ￥617.9/50mg ￥184.9/5mg ￥3649.0/250g
- 纯度：95.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：2-(4-(叔丁基)苯基)-1H-苯并[d]咪唑
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：97.0%
- 备货期：需询单
- 联系人：王汐瑶
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参考价格：$66/10mM*1mLinDMSO