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Apramycin

更新时间:2024-07-15 12:35:00 采购访问:9次

常用名 阿布拉霉素 CAS号 37321-09-8
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine. IC50 value:Target: Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. The drug binds in the deep groove of the RNA which forms a continuously stacked helix comprising non-canonical C.A and G.A base pairs and a bulged-out adenine. The binding mode of apramycin at the human decoding-site RNA is distinct from aminoglycoside recognition of the bacterial target, suggesting a molecular basis for the actions of apramycin in eukaryotes and bacteria.
物理化学性质:
CAS号:37321-09-8
常用中文名:阿布拉霉素
常用英文名:Apramycin
分子式:C21H41N5O11
分子量:539.57700
密度:1.56 g/cm3
沸点:823ºC at 760 mmHg
熔点:N/A
闪点:451.6ºC

供应商信息

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