| 常用名 | SR31527 | CAS号 | 311814-78-5 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: SR31527 is a novel allosteric Kinesin-like protein KIFC1 inhibitor that inhibits microtubule-stimulated KIFC1 ATPase activity with IC50 of 6.6 uM, binds directly to KIFC1 with Kd of 25.4 nM; prevents bipolar clustering of extra centrosomes in TNBC cells and significantly reducesTNBC cell colony formation and viability (MDA-MB-231, BT549 and MDA-MB-435s cells IC50=20-30 uM), with less toxicity to normal fibroblasts. 物理化学性质: CAS号:311814-78-5 常用中文名:SR31527 常用英文名:SR31527 分子式:C15H14ClN3OS 分子量:319.807 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |