LCB 03-0110 dihydrochloride
更新时间：2024-07-15 12:33:20
采购访问：18次
| 常用名 | LCB 03-0110 dihydrochloride | CAS号 | 1962928-28-4 |
|---|---|---|---|
| 价格 | 纯度 | 99.76% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： LCB 03-0110 is a potent, ATP-competitive inhibitor of Discoidin domain receptor (DDR) family and c-Src tyrosine kinase family, as well as Btk and Syk; potently inhibits the activated tyrosine kinase activity of DDR2 (IC50=6 nM), and nonactivated form of DDR2 (IC50=145 nM); suppresses collagen-induced autophosphorylation of DDR1 and DDR2 with IC50 of 164 and 171 nM in cell-based assays; inhibits all eight Src family kinases with IC50 of 2-20 nM; suppresses the proliferation and migration of primary dermal fibroblasts induced by TGF β1 and type I collagen (IC50=194 nM), inhibits cell migration and nitric oxide, iNOS, COX2, and TNF-α synthesis in LPS-activated J774A.1 macrophage cells; suppresses hypertrophic scar formation in wound healing models. 物理化学性质： CAS号：1962928-28-4 常用中文名：LCB 03-0110 dihydrochloride 常用英文名：LCB 03-0110 dihydrochloride 分子式：C24H25Cl2N3O2S 分子量：490.443 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
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