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纺锤菌素二盐酸

更新时间:2024-07-15 12:33:02 采购访问:7次

常用名 纺锤菌素二盐酸 CAS号 18133-22-7
价格 纯度 96.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Netropsin (dihydrochloride) is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei[1]. Netropsin (dihydrochloride) has potential antibiotic and antiviral properties by binding to dsDNA in a non-intercalative manner, it improves survival from murine endotoxaemia by attenuating NOS2 induction through interference with HMGA1 DNA binding to the core NOS2 promoter[2]. Netropsin (dihydrochloride) in solutions of DNA has radioprotective ability against radiation-induced damage due to its high binding affinity and high structural stabilization, hydroxyl radical (OH*) generated by ionizing radiation cannot radiolyse the netropsin-DNA complex[3].
物理化学性质:
CAS号:18133-22-7
常用中文名:纺锤菌素二盐酸
常用英文名:Netropsin dihydrochloride
分子式:C18H28Cl2N10O3
分子量:466.92500
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:-20°C

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2024-03-12 纺锤菌素 二盐酸盐
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