常用名 | 依来努单抗 | CAS号 | 1791416-49-3 |
---|---|---|---|
价格 | 纯度 | 97.4% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC50 around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism[1][2]. 物理化学性质: CAS号:1791416-49-3 常用中文名:依来努单抗 常用英文名:Elezanumab 分子式: 分子量: 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |