| 常用名 | 丙硫异烟胺 | CAS号 | 14222-60-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis; has also been tested for use in the treatment of leprosy.Target: Anti tuberculosisAlthough ETH and PTH are both potent drugs against M. tuberculosis (MIC = ~0.5 μg/ml) (24), they do not affect E. coli growth, even at very high concentrations (100 μg/ml), which is primarily caused by the absence of an EthA homologue in E. coli [1]. Clinical improvement was noted in 74% of the patients treated with ethionamide and in 83% of those treated with prothionamide. Therapy was well tolerated and drug-related hepatotoxicity did not require discontinuation of therapy. The 500-mg dose of both ethionamide and prothionamide resulted in loss in Mycobacterium leprae viability more rapidly than did the 250-mg dose, and prothionamide at both dose levels was superior to the equivalent dose of ethionamide [2]. 物理化学性质: CAS号:14222-60-7 常用中文名:丙硫异烟胺 常用英文名:protionamide 分子式:C9H12N2S 分子量:180.270 密度:1.1±0.1 g/cm3 沸点:310.4±44.0 °C at 760 mmHg 熔点:140ºC 闪点:141.5±28.4 °C 储存条件:Refrigerator |