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SR 1903

更新时间:2024-07-15 12:31:57 采购访问:13次

常用名 SR 1903 CAS号 1414248-06-8
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1). It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity.
物理化学性质:
CAS号:1414248-06-8
常用中文名:SR 1903
常用英文名:SR 1903
分子式:C27H27F6N3O
分子量:523.513
密度:1.3±0.1 g/cm3
沸点:559.0±50.0 °C at 760 mmHg
熔点:N/A
闪点:291.9±30.1 °C

供应商信息

上海念兴实业有限公司 认证供应商

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商品数:403768件
电话:18916513247
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地区: 上海市 上海市 普陀区
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联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
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2021-04-03 SR 1903
价格:¥2842.0

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