| 常用名 | HuR inhibitor KH-3 | CAS号 | 1215115-03-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: HuR inhibitor KH-3 is a small molecule, selective inhibitior of HuR function with Ki of 0.83 and 0.72 uM in FP and AlphaLISA assays, respectively.KH-3 potently inhibits breast cancer cell growth in vitro and in vivo.KH-3 inhibits breast cancer cell invasion in vitro as well as delays initiation of lung colonies and improves mouse survival in an experimental metastasis model in vivo.KH-3 suppresses breast cancer cell invasion by disrupting HuR-FOXQ1 mRNA interaction.Inhibition of HuR with KH-3 yielded a significant reduced in the progression of pathological cardiac hypertrophy in a transverse aortic constriction model. 物理化学性质: CAS号:1215115-03-9 常用中文名:HuR inhibitor KH-3 常用英文名:HuR inhibitor KH-3 分子式:C21H22N2O4S2 分子量:430.537 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |