| 常用名 | EM 163 | CAS号 | 1206480-93-4 |
|---|---|---|---|
| 价格 | 纯度 | 99.07% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: EM 163 is a TIR-TIR interaction inhibitor, which is a TIR (Toll/interleukin-1 receptor) structural domain mimic of the MyD88 protein. EM 163 targets the TIR structural domain in the IL-1 receptor and blocks the interaction with MyD88. EM 163 inhibits the production of inflammatory cytokines in vivo caused by staphylococcal enterotoxin B (SEB). EM 163 protects mice from SEB shock-induced death. In rat hippocampal neurons in vitro, EM 163 blocked the activation of p38 and the inhibitory effect of IL-1β on chemically induced long-term potentiation (LTP)-triggered protein synthesis. 物理化学性质: CAS号:1206480-93-4 常用中文名:EM 163 常用英文名:EM 163 分子式:C44H60IN5O4 分子量:849.88 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |