常用名 | 多非利特 | CAS号 | 115256-11-6 |
---|---|---|---|
价格 | 纯度 | 98.0% | |
备货期 | 10天 | 库存 | 现货 |
产品详情(用途,包装等)
用途: Dofetilide(Tikosyn) is a class III antiarrhythmic agent.Target: Potassium ChannelIn patients with congestive heart failure and reduced left ventricular function, dofetilide was effective in converting atrial fibrillation, preventing its recurrence, and reducing the risk of hospitalization for worsening heart failure. Dofetilide had no effect on mortality [1]. dofetilide preferentially blocks open (or activated) channels and that the fast inactivation may competitively slow the binding kinetics. Dofetilide acts as a slow-onset/slow-offset open channel blocker of this current at nanomolar concentrations [2]. 物理化学性质: CAS号:115256-11-6 常用中文名:多非利特 常用英文名:Dofetilide 分子式:C19H27N3O5S2 分子量:441.565 密度:1.3±0.1 g/cm3 沸点:614.1±65.0 °C at 760 mmHg 熔点:147-1490C 闪点:325.2±34.3 °C 储存条件:Store at RT |