| 常用名 | SNX-0723 | CAS号 | 1073969-18-2 |
|---|---|---|---|
| 价格 | 纯度 | 99.86% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: SNX-0723 is a selective, brain-permeable, orally acitve small-molecule inhibitor of Hsp90 (IC50=14 nM) that inhibits alpha-synuclein oligomerization with EC50 of 48 nM; induces Hsp70 (IC50=31 nM), and decreases expression of several known Hsp90 client proteins:HER2 (IC50=9.4 nM), ribosomal protein s6 (pS6) (IC50=13 nM), and PERK (IC50=5.5 nM); shows significant brain concentrations along with induction of brain Hsp70 in vivo with promising PK properties. 物理化学性质: CAS号:1073969-18-2 常用中文名:SNX-0723 常用英文名:SNX-0723 分子式:C22H26FN3O3 分子量:399.47 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |