| 常用名 | AS 2444697 | CAS号 | 1287665-60-4 |
|---|---|---|---|
| 价格 | ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: A potent, selective, orally bioavailable IRAK-4 inhibitor that potently inhibits human and rat IRAK-4 activity with subnanomolar order, >30-fold selectivity over IRAK-1; inhibited IL-1β- or TLR ligand lipopolysaccharide (LPS)-induced IL-6 production in human lung alveolar epithelial cells, fibroblast-like synoviocytes, and peripheral blood mononuclear cells; significantly reduces urinary protein excretion and preventd the development of glomerulosclerosis and interstitial fibrosis without affecting the blood pressure in mice model of chronic kidney disease. 物理化学性质: CAS号:1287665-60-4 常用中文名:AS 2444697 常用英文名:AS 2444697 分子式:C19H21ClN6O4 分子量:432.861 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:室温,干燥,密封 |