5-羟基-4-甲氧基铁屎米酮

更新时间：2025-08-26 21:25:09

5-羟基-4-甲氧基铁屎米酮结构式	常用名	5-羟基-4-甲氧基铁屎米酮	英文名	5-Hydroxy-4-methoxycanthin-6-one
	CAS号	18110-86-6	分子量	266.251
	密度	1.5±0.1 g/cm3	沸点	442.7±45.0 °C at 760 mmHg
	分子式	C₁₅H₁₀N₂O₃	熔点	N/A
	MSDS	N/A	闪点	221.5±28.7 °C

5-羟基-4-甲氧基铁屎米酮用途

Nigakinone 是苦木中含量最丰富的生物碱之一,具有重要的药理活性。

中文名	苦木碱乙
英文名	Nigakinone
中文别名	5-羟基-4-甲氧基铁屎米酮 \| 苦木酮碱 \| 苦木碱己
英文别名	更多

描述	Nigakinone 是苦木中含量最丰富的生物碱之一,具有重要的药理活性。
相关类别	信号通路 >> 其他 >> 其他天然产物 >> 生物碱研究领域 >> 其他
参考文献	[1]. Wang N, et al. Quality Assessment of Kumu Injection, a Traditional Chinese Medicine Preparation, Using HPLC Combined with Chemometric Methods and Qualitative and Quantitative Analysis of Multiple Alkaloids by Single Marker. Molecules. 2018 Apr 9;23(4).

密度	1.5±0.1 g/cm3
沸点	442.7±45.0 °C at 760 mmHg
分子式	C₁₅H₁₀N₂O₃
分子量	266.251
闪点	221.5±28.7 °C
精确质量	266.069153
PSA	63.83000
LogP	1.92
InChIKey	PGFKZUOYIFDMQJ-UHFFFAOYSA-N
SMILES	COc1c(O)c(=O)n2c3ccccc3c3ccnc1c32
外观性状	黄色粉末
蒸汽压	0.0±1.1 mmHg at 25°C
折射率	1.747
储存条件	2-8℃，干燥，密闭

危害码 (欧洲)	Xi
海关编码	2933990090

5-羟基-4-甲氧基铁屎米酮上游产品 0
5-羟基-4-甲氧基铁屎米酮下游产品 3
CAS号18110-87-7 4,5-二甲氧基铁屎米酮 CAS号3464-66-2 苦木碱B；1-甲氧基羰基-beta-咔啉 CAS号17337-22-3 9H-吡啶并[3,4-b]吲哚-1-甲醇

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th...
来源：Johns Hopkins Ion Channel Center
靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源：The Scripps Research Institute Molecular Screening Center
靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源：The Scripps Research Institute Molecular Screening Center
靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源：Burnham Center for Chemical Genomics
靶标：N/A
External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源：Broad Institute
靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源：Broad Institute
靶标：N/A
External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源：The Scripps Research Institute Molecular Screening Center
靶标：muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源：The Scripps Research Institute Molecular Screening Center
靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti...
来源：The Scripps Research Institute Molecular Screening Center
靶标：caspase-3 preproprotein [Homo sapiens]
External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

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