| 常用名 | PTC596 | CAS号 | 1610964-64-1 |
|---|---|---|---|
| 价格 | ¥需询单/1g ¥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: PTC596 is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) inhibitor. PTC596 targets BMI1 expressed by both tumor cells and cancer stem cells (CSCs), and induces hyper-phosphorylation of BMI1, leading to its degradation. PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells[1][2]. 物理化学性质: CAS号:1610964-64-1 常用中文名:PTC596 常用英文名:PTC596 分子式:C19H13F5N6 分子量:420.339 密度:1.6±0.1 g/cm3 沸点:583.9±60.0 °C at 760 mmHg 熔点:N/A 闪点:307.0±32.9 °C 储存条件:-20°C,密闭,干燥 |