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IB-MECA

更新时间:2025-08-21 21:30:20

常用名 匹利诺生 CAS号 152918-18-8
价格 ¥需询单/1g 纯度 98.0%
备货期 1天 库存 现货
 产品详情(用途,包装等)
用途:
Piclidenoson (IB-MECA) is an agonist of the adenosine A3 receptor with EC50 values of 0.11 μM. IC50 value: 0.11 μM (EC50) [3]Target: adenosine A3 receptorin vitro: Piclidenoson has been shown to play important roles in cell proliferation and apoptosis in a variety of cancer cell lines. ThePiclidenoson was capable of decreasing intracellular cyclic adenosine monophosphate (cAMP) that was the reason for the presence of functional A3 adenosine receptor on the cell lines. Piclidenoson significantly reduced cell viability in a dose-dependent manner. Piclidenoson, an A3AR agonist, inhibits the growth of different cancer cell types like melanoma, colon, breast, leukemia, and prostatePiclidenoson was able to inhibit forskolin-stimulated cAMP levels with an EC50 value of 0.82 μM in OVCAR-3 cells. Piclidenoson was able to inhibit forskolin-stimulated cAMP levels with an EC50 value of 1.2 μM in Caov-4 cells.in vivo: Administrations of single intraperitoneal doses of either Piclidenoson 0.5 h post-irradiation resulted in statistically significant increases of MST in comparison with the control irradiated mice.[2]
物理化学性质:
CAS号:152918-18-8
常用中文名:匹利诺生
常用英文名:IB-MECA
分子式:C18H19IN6O4
分子量:510.286
密度:2.0±0.1 g/cm3
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8°C,避光干燥密封

供应商信息

武汉敬康恩生物医药科技有限公司

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电话:15871494362
地址:光谷大道58号
地区: 湖北省 武汉市 东西湖区
联系人:周经理
联系人电话:15871494362
邮件:orders@jknbiochem.com
网址:http://www.jknbiochem.com
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参考价格:$189/10mM*1mLinDMSO
其他供应商价格:
2024-07-15 (2S,3S,4R,5R)-3,4-二羟基-5-(6-((3-碘苄基)氨基)-9H-嘌呤-9-基)-N-甲基四氢呋喃-2-甲酰胺
价格:需询单
2022-11-29 IB-MECA
价格:¥需询单
2021-04-03 Piclidenoson
价格:¥3150.0
2022-02-19 IB-MECA
价格:¥988.9
2023-09-26 IB-MECA
价格:¥需询单

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