常用名 | NNC 05-2090 | CAS号 | 184845-43-0 |
---|---|---|---|
价格 | ¥需询单/1g | 纯度 | 98.9% |
备货期 | 1天 | 库存 | 现货 |
产品详情(用途,包装等)
NNC052090 is a GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). NNC052090 inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. NNC052090 also displays affinity at α1- and D2-receptors (IC50 values are 266 and 1632 nM respectively). |